Overview of Relationship Between Antibody And Psoriasis Arthritis

Antibodies have been shown to have good sensitivity and specificity for rheumatoid arthritis (RA) and are closely associated with joint destruction and prognosis of RA. 

Therefore, custom antibodies have become a serological marker widely used in the clinical diagnosis of RA. However, custom antibody online can also be present in the serum of a patient with psoriatic arthritis.

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Studies abroad have found that antibodies can be found in the serum of patients with psoriatic arthritis, and the positive rate is 8% to 13.11%, both higher than expected.

Domestic Pan Hong et al found 56 cases of PsA patients in 56 cases of psoriatic arthritis, the positive rate of antibody was 12.5%, and the positive rate of symmetrical polyarthritis type was 21.4%, significantly higher than The other four clinical types (P<0.05) were significantly higher than the healthy control group (0%) but lower than the RA patients (84.7%), which was consistent with foreign reports; the number of swollen joints, wrist involvement, and ESR was positive in antibody. 

Although PSA is classified as seronegative spondyloarthropathy, there are still a certain number of patients with PsA who are positive for antibodies. Therefore, it is not possible to exclude the diagnosis of PsA based on anti-CCP antibody positive, but whether or not these diseases develop into bone. Destroy a serological indicator and become a prognostic indicator.

The detection rate of antibodies in patients with PsA was significantly lower than that in patients with RA. Among the five clinical types of PsA patients, the positive rate of antibodies in symmetrical polyarthritis patients was the highest (21.4%), while the other four types were the other. It is only sporadic and therefore contributes to clinical typing in patients with PSA.

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